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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TDRKH
All Species:
0
Human Site:
T167
Identified Species:
0
UniProt:
Q9Y2W6
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y2W6
NP_001077434.1
606
67025
T167
C
D
K
E
S
E
G
T
L
L
L
S
R
L
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001108076
573
62636
V143
P
V
S
E
Q
L
S
V
P
Q
R
S
V
G
R
Dog
Lupus familis
XP_851426
551
60647
L129
N
T
P
V
S
E
Q
L
S
V
P
Q
R
S
V
Cat
Felis silvestris
Mouse
Mus musculus
Q80VL1
560
62116
R138
V
P
Q
R
S
V
G
R
I
I
G
R
G
G
E
Rat
Rattus norvegicus
XP_227438
560
61993
R138
V
P
Q
R
S
V
G
R
I
I
G
R
G
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514669
319
34334
Chicken
Gallus gallus
XP_423400
665
71440
I144
R
E
L
S
G
R
I
I
G
H
G
G
E
T
V
Frog
Xenopus laevis
NP_001089292
718
79433
G158
G
R
I
I
G
Q
G
G
E
R
I
R
A
I
T
Zebra Danio
Brachydanio rerio
NP_001014377
573
63662
L144
I
L
I
A
Q
C
A
L
E
K
L
A
T
D
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608657
576
63805
A148
L
Q
V
P
Q
R
L
A
S
K
I
N
G
R
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785759
489
55090
E67
V
G
P
L
I
G
R
E
G
I
N
I
K
R
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
85.3
82.6
N.A.
84.8
85.8
N.A.
29.8
39
36.3
38.2
N.A.
23.9
N.A.
N.A.
33.1
Protein Similarity:
100
N.A.
87.1
85.9
N.A.
88.1
88.6
N.A.
39.1
53.3
54.8
57.4
N.A.
42.5
N.A.
N.A.
49.6
P-Site Identity:
100
N.A.
13.3
20
N.A.
13.3
13.3
N.A.
0
0
6.6
6.6
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
13.3
33.3
N.A.
33.3
33.3
N.A.
0
13.3
26.6
13.3
N.A.
13.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
10
10
0
0
0
10
10
0
0
% A
% Cys:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% D
% Glu:
0
10
0
19
0
19
0
10
19
0
0
0
10
0
19
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
19
10
37
10
19
0
28
10
28
28
10
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
10
0
19
10
10
0
10
10
19
28
19
10
0
10
19
% I
% Lys:
0
0
10
0
0
0
0
0
0
19
0
0
10
0
0
% K
% Leu:
10
10
10
10
0
10
10
19
10
10
19
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% N
% Pro:
10
19
19
10
0
0
0
0
10
0
10
0
0
0
0
% P
% Gln:
0
10
19
0
28
10
10
0
0
10
0
10
0
0
0
% Q
% Arg:
10
10
0
19
0
19
10
19
0
10
10
28
19
19
10
% R
% Ser:
0
0
10
10
37
0
10
0
19
0
0
19
0
10
0
% S
% Thr:
0
10
0
0
0
0
0
10
0
0
0
0
10
10
10
% T
% Val:
28
10
10
10
0
19
0
10
0
10
0
0
10
0
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _